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Volume 1 of this two volume set focuses on techniques for studying cell structure. It describes light and electron microscopy, subcellular fractionation, protein purification and analysis, nucleic acid analysis, lipid analysis, and investigations of the cytoskeleton. Volume 2 concentrates on understanding how cells function. It describes a range of key investigations of cell function including analyses of gene expression, the cell cycle, cellular bioenergetics, transport across the nuclear membrane and the ER membrane, endosome transport, receptors, and signal transduction.
Essential Cell Biology provides a readily accessible introduction to the central concepts of cell biology, and its lively, clear writing and exceptional illustrations make it the ideal textbook for a first course in both cell and molecular biology. The text and figures are easy-to-follow, accurate, clear, and engaging for the introductory student. Molecular detail has been kept to a minimum in order to provide the reader with a cohesive conceptual framework for the basic science that underlies our current understanding of all of biology, including the biomedical sciences. The Fourth Edition has been thoroughly revised, and covers the latest developments in this fast-moving field, yet retains the academic level and length of the previous edition. The book is accompanied by a rich package of online student and instructor resources, including over 130 narrated movies, an expanded and updated Question Bank. Essential Cell Biology, Fourth Edition is additionally supported by the Garland Science Learning System. This homework platform is designed to evaluate and improve student performance and allows instructors to select assignments on specific topics and review the performance of the entire class, as well as individual students, via the instructor dashboard. Students receive immediate feedback on their mastery of the topics, and will be better prepared for lectures and classroom discussions. The user-friendly system provides a convenient way to engage students while assessing progress. Performance data can be used to tailor classroom discussion, activities, and lectures to address students’ needs precisely and efficiently. For more information and sample material, visit http://garlandscience.rocketmix.com/.
This text features lively, clear writing and exceptional illustrations, making it the ideal textbook for a first course in both cell and molecular biology. Thoroughly revised and updated, the Fifth Edition maintains its focus on the latest cell biology research. For the first time ever, Essential Cell Biology will come with access to Smartwork5, Norton's innovative online homework platform, creating a more complete learning experience.
Biological and medical research relies upon an integrated understanding of the molecules within cells and of the interactions between cells. This has imposed great demands on investigators. Being an expert in a relatively narrow area is no longer sufficient as many studies now require the use of a wide range of techniques to provide the necessary integration. A lack of familiarity with the experimental possibilities can make such diversification difficult to achieve. This two volume set of Essential Cell Biology is designed to help researchers overcome these problems. It has not been possible to include all of the techniques available in cell biology so the challenge was to identify those that might be most relevant to researchers who are new to this topic. We have tried to cover both traditional and more recent approaches. The theory and basic principles of each technique are described, together with detailed protocols and advice for trouble shooting. Directions to more specialised techniques are also included. We hope the result inspires readers to experience the challenges and rewards of cell biology research for themselves and to contribute to the ongoing task of understanding the life of the cell. Essential Cell Biology volume 2 concentrates on understanding how the cell functions whilst Volume 1 focuses on techniques for studying cell structure. Volume 2 details the essential background information and protocols for investigating cell cell function, including, for example, investigations of cellular transport, receptors and gene expression. This is the essential guide to cell biology for researchers new to the field.
Master the important pathophysiology concepts you need to know with the most engaging and reader-friendly text available. Filled with vibrant illustrations and complemented by online resources that bring pathophysiology concepts to life, Understanding Pathophysiology, 6th Edition continues its tradition of delivering the most accurate information on treatments, manifestations, and mechanisms of disease across the lifespan, giving you the fundamental knowledge needed to move forward in your nursing education and career. New additions include a new chapter on epigenetics, new content on rare diseases, a separate chapter for male and female reproductive alterations, streamlined features, simplified language, and fully updated information throughout. Introduction to Pathophysiology in the front matter section provides intro to the subject of pathophysiology and explains why it is important. Consistent presentation helps readers better distinguish pathophysiology, clinical manifestations, and evaluation and treatment for each disease. More than 1,000 high-quality illustrations vividly depict clinical manifestations and cellular mechanisms underlying diseases. Lifespan coverage details age-specific conditions affecting pediatric, adult, and aging patients in depth. Algorithms throughout the text clarify disease progression. Risk Factor boxes alert readers to important safety considerations associated with specific diseases. Health Alert boxes highlight new developments in biologic research, diagnostic studies, preventive care, treatments, and more. Quick Check boxes test readers’ retention of important chapter concepts. Geriatric Considerations boxes and Pediatric Considerations boxes highlight key considerations for these demographics in relevant chapters. Did You Understand? sections provide a fast and efficient review of chapter content. Chapter outlines help readers find specific information with ease. Chapter introductions explain why chapter content is important and how it fits into a broader health care context. Key terms are bolded throughout the text for fast, easy reference. Glossary of selected terms familiarizes readers with the most difficult or important terminology. Additional online resources on Evolve companion website offers access to animations, review questions, key terms matching exercises, and more.
This examination of stem cell biology from a philosophy of science perspective clarifies the field's central concept, the stem cell, as well as its aims, methods, models, explanations and evidential challenges. Relations to systems biology and clinical medicine are also discussed.
Updated and more efficient techniques for the culture of animal cells are presented here in a step-by-step format supported by a notes section offering troubleshooting advice with hints and tips developed to guarantee the successful culture of animal cells.
There has been a huge increase in the knowledge and understanding of the immunological processes involved in surgical practice in recent years. Anaesthesiologists and intensive care physicians are increasingly recognising the significant derangements of immune function in the critically ill patient and the possible therapeutic approaches to manage such patients (including new approaches in transplantation rejections, novel vaccination strategies in cancer treatment, as well as a better understanding of the beneficial effects of standard chemotherapy). Written by recognised experts in their field from both the UK and the US, and extensively referenced for further reading, Essential Immunology for Surgeons provides a concise, up-to-date, and readable account of immunology in general and its translation into key areas of clinical practice. It provides the necessary foundation for a critical understanding of this essential and rapidly expanding area of biological science that underpins and explains the modern concepts of a range of diseases and conditions, encompassing autoimmunity, infection, trauma, cancer, nutrition, organ transplantation, and various forms of therapy. Previously published as Immunological Basis for Surgical Science and Practice, this fully-updated textbook is aimed predominantly at the surgical trainee, but will also be of value to undergraduate and postgraduate clinicians of any discipline who wish to have a better understanding and knowledge of the subject, as well as to researchers studying the various core topics discussed in the book.